The Ultimate Guide to Weight Loss with Semaglutide


Semaglutide is a medication that has gained significant attention in recent years due to its potential to aid weight loss. It is a peptide that mimics the actions of the naturally occurring hormone GLP-1, which helps regulate blood sugar levels. While originally approved to treat Type 2 Diabetes, semaglutide has been shown to have significant medical weight loss benefits in clinical trials, leading to its approval for weight management in certain patients.




What is Semaglutide?

This is a medication used to treat Type 2 Diabetes and obesity, and it belongs to a class of drugs known as GLP-1 receptor agonists. It works by stimulating the production of insulin and reducing the release of glucagon in the body. Semaglutide goes by brand names such as Ozempic, Rebylsus, and Wegovy, which are all peptides for weight loss.


Dosage of Semaglutide for weight loss

The dosage of Semaglutide varies depending on the individual's condition and response to treatment. The medication is administered as an injection under the skin once a week. The usual starting dose is 0.25 mg once a week, which can be increased to 1 mg once a week if needed.

The recommended dose should be taken once a week, on the same day and at the same time each week. The medication should be injected subcutaneously in the abdomen, thigh, or upper arm. The injection site should be rotated to reduce the risk of skin reactions.


Benefits of Semaglutide

Semaglutide has been found to be effective in promoting weight loss in both diabetic and non-diabetic individuals. A recent study published in the New England Journal of Medicine showed that Semaglutide led to an average weight loss of 15% among obese adults, which is significantly higher than other weight loss drugs currently available in the market. Semaglutide works by reducing appetite, increasing feelings of fullness, and slowing down the rate at which food leaves the stomach. These effects can help people eat less and reduce their caloric intake, leading to weight loss over time.


Side Effects of Semaglutide

Like any medication, Semaglutide can cause side effects. The most common side effects include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Constipation
  • Dizziness
  • Fatigue

Most of these side effects are mild and will go away on their own. However, if you experience severe or persistent side effects, you should contact your doctor.

Less common but more severe side effects may include:

  • Acute Pancreatitis: Semaglutide has been associated with an increased risk of acute pancreatitis, a potentially life-threatening condition that causes inflammation of the pancreas.
  • Diabetic Retinopathy: There have been reports of worsening of diabetic retinopathy in some people using Semaglutide. Diabetic retinopathy is a complication of diabetes that can cause vision loss and blindness.
  • Gallbladder disease can be a rare but serious side effect of Semaglutide.
  • Semaglutide may also affect kidney function in some people.
  • Severe allergic reactions to Semaglutide are possible, but rare.

If you experience any of these serious side effects, you should seek medical attention immediately.



Semaglutide is an injectable medication used to treat type 2 diabetes and is FDA approved as a weight loss medication. It has been shown to have several benefits, including improved blood sugar control, weight loss, and cardiovascular benefits. However, like any medication, it can cause side effects, and it is important to follow your healthcare provider's instructions and precautions. If you have any concerns or questions about Semaglutide, please consult your healthcare provider.

Performance Pain and Sports Medicine has consultations for Semaglutide available via telemedicine for residents of all 50 states (so visit our online store now), or you can see Dr. Suzanne Manzi in person at the Houston or League City locations in Texas. Contact us now to learn more.

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