Pain Management in Lawrenceville, NJ

Chronic pain affects approximately 60 million Americans, limiting daily activities and reducing quality of life (NCHS Data Brief, 2024). Many patients in the Lawrenceville and Central New Jersey area have spent months or years managing pain with medications that provide only temporary relief, while the underlying problem continues to limit what they can do. If this sounds familiar, you are not alone, and you do not have to accept chronic pain as permanent.

Performance Pain and Sports Medicine provides advanced, non-surgical pain management for patients throughout Lawrenceville, the Greater Princeton area, Mercer County, and the surrounding tri-state region. The Lawrenceville clinic focuses on treating the source of pain through minimally invasive, evidence-based procedures rather than relying on long-term medication management alone.

This location is the only Performance Pain and Sports Medicine office in the Northeast and one of only two locations nationwide offering the Discseel® Procedure, a regenerative approach to disc repair. Dr. Matthias Wiederholz, MD, one of a small handful of Master Discseel® Instructors worldwide, was the first physician to bring Discseel® to New Jersey.

Whether back pain, neck pain, nerve pain, joint pain, or chronic headaches have started affecting your ability to work, exercise, or enjoy time with family, the Lawrenceville office is here to help you find a path forward.

Schedule Your Consultation | Call 609-588-8600

What Is Interventional Pain Management?

When chronic pain persists, patients typically encounter three treatment paths. Medication management can reduce symptoms but does not address the underlying cause. Surgery carries significant risks and lengthy recovery periods, and is not always appropriate. Interventional pain management offers a third path: minimally invasive, image-guided procedures that target pain at its source.

Rather than managing symptoms indefinitely, interventional pain management delivers treatment directly to the affected nerve, joint, or disc. These procedures are typically performed on an outpatient basis, often with only local anesthesia or light sedation. For patients who have been told that stronger medications or surgery are their only remaining options, this approach may offer a middle ground that many are not aware exists.

The American Society of Interventional Pain Physicians (ASIPP) has published comprehensive evidence-based guidelines supporting these procedures for managing chronic spinal pain (ASIPP Clinical Guidelines, 2021) and emphasizes them as preferred alternatives to long-term opioid therapy (ASIPP Opioid Guidelines, 2023).

The goal is not simply pain reduction. It is restoring enough function to return to the activities that matter most, whether that means getting back to work, exercising, playing with children or grandchildren, or sleeping through the night without waking in pain.

Conditions Treated at Our Lawrenceville Pain Management Clinic

Performance Pain and Sports Medicine evaluates and treats a wide range of chronic and acute pain conditions. Each patient receives a thorough diagnostic assessment before any treatment plan is developed.

Back Pain and Spine Conditions

Low back pain is the leading cause of disability worldwide (Lancet GBD, 2023). For patients whose back pain has progressed from an occasional ache to a daily limitation, a targeted evaluation can identify the specific structure causing the problem. The Lawrenceville clinic treats herniated discs, degenerative disc disease, spinal stenosis, sciatica, annular tears, and failed back surgery syndrome.

Neck Pain

Cervical disc problems, whiplash injuries, and cervicogenic headaches can gradually erode quality of life when left unaddressed. Patients often notice that neck pain starts to limit their ability to drive, work at a computer, or sleep comfortably. Treatment options range from targeted injections to advanced nerve ablation procedures. Neck pain treatment

Joint Pain

Knee, hip, and shoulder pain from osteoarthritis or overuse conditions may respond well to image-guided injections and regenerative therapies. For patients who have been told that joint replacement is their next step, minimally invasive options may help delay or avoid surgery. Joint injections

Nerve Pain and Neuropathy

Peripheral neuropathy, radiculopathy, and complex regional pain syndrome (CRPS) can be among the most difficult pain conditions to manage with medication alone. Targeted nerve blocks and neuromodulation therapies offer approaches that address nerve pain at the source. Nerve pain treatment

Headaches and Migraines

Chronic migraines and cervicogenic headaches that have not responded to standard medications may benefit from nerve blocks and chemodenervation treatments. Identifying whether the headache originates from cervical spine dysfunction or another source is a critical first step. Headache treatment

Our Approach to Pain Treatment

Treatment at the Lawrenceville clinic follows a structured pathway: accurate diagnosis first, then targeted intervention. Patients who have cycled through generic treatment plans without lasting improvement often find that the missing piece was a precise diagnosis of which structure is actually generating the pain.

Diagnostic Testing

Advanced imaging review and electrodiagnostic testing help evaluate nerve and muscle function, ensuring every procedure targets the correct structure. For patients whose MRI has been read as “normal” despite ongoing symptoms, additional diagnostic tools can sometimes reveal annular tears, subtle nerve compression, or joint dysfunction that standard reads may miss.

Injection Therapies

Targeted injections deliver anti-inflammatory medication directly to the source of pain. Epidural steroid injections (transforaminal, interlaminar, and caudal approaches), facet joint injections, medial branch blocks, sacroiliac joint injections, and peripheral nerve blocks are among the most commonly performed procedures. Clinical evidence supports their efficacy for managing radicular pain and reducing reliance on oral medications (Goel et al., Journal of Pharmacy and Bioallied Sciences, 2023).

Advanced Pain Procedures

Radiofrequency ablation (RFA) uses targeted heat energy to interrupt pain signaling from specific nerves. Systematic reviews have demonstrated sustained pain reduction at six months and beyond for patients with facet-mediated back pain (Du et al., European Spine Journal, 2024). Spinal cord stimulation (SCS), an option for patients with chronic pain that has not responded to other interventions, was associated with superior outcomes compared to conventional medical management in a network meta-analysis of 13 randomized trials involving over 1,500 patients (Huygen et al., JAMA Network Open, 2024). The Lawrenceville clinic also offers intrathecal pain pumps and the Intracept procedure for vertebrogenic back pain.

Regenerative Medicine

For patients seeking to repair damaged tissue rather than manage symptoms long-term, regenerative approaches may offer an alternative path. PRP (platelet-rich plasma) therapy concentrates the body’s own healing factors and delivers them to injured joints, tendons, or spinal structures. The Discseel® Procedure, available exclusively at the Lawrenceville and Houston locations, uses a biologic fibrin sealant to seal damaged spinal discs and promote tissue regeneration. For patients who have been recommended for spinal fusion but want to explore non-surgical options first, Discseel® may offer a path worth evaluating.

Procedures Available at Our Lawrenceville Clinic

Meet Your Lawrenceville Pain Management Provider

The Lawrenceville office is led by Dr. Matthias Wiederholz, MD, Founder of Performance Pain and Sports Medicine. Dr. Wiederholz is board-certified in Physical Medicine and Rehabilitation, Pain Medicine, Sports Medicine, and Anti-Aging, Regenerative and Functional Medicine.

Dr. Wiederholz established Performance Pain and Sports Medicine in 2009 with a focus on repairing the source of pain through minimally invasive and regenerative approaches rather than relying on long-term medication or surgery. He completed his residency in Physical Medicine and Rehabilitation at Baylor College of Medicine in Houston, where he served as Chief Resident, followed by a fellowship in Interventional Pain Management and Sports Medicine in Marietta, Georgia.

In 2020, Dr. Wiederholz became the first physician to bring the Discseel® Procedure to New Jersey after training directly under its inventor, Dr. Kevin Pauza. He holds the designation of Master Discseel® Instructor, one of a small handful of Master Discseel® Instructors worldwide, and trains other physicians in the technique internationally. He has also personally undergone the Discseel® Procedure, giving him a firsthand understanding of the recovery process that directly informs how he counsels patients.

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Performance Pain and Sports Medicine is a multi-location practice with additional offices in Houston, Baytown, and League City, Texas, where patients also have access to Dr. Suzanne Manzi, MD, Co-Founder, who specializes in interventional pain management, electrodiagnostic medicine, and obesity medicine.

Visit Our Lawrenceville Pain Management Clinic

The Lawrenceville office provides convenient access for patients throughout Central New Jersey, the Greater Princeton area, and the tri-state region, including patients traveling from New York and Pennsylvania.

Performance Pain and Sports Medicine
4056 Quakerbridge Road, Suite 112
Lawrenceville, NJ 08648

Phone: 609-588-8600

Landmark: The office is located in the building complex shared with Silver Pharmacy and Jag Physical Therapy on Quakerbridge Road, approximately one mile from Quakerbridge Mall.

Driving Directions:

  • From Route 1: Travel south on Quakerbridge Road. The office is on the right, just after Costco.
  • From Hamilton: Travel north on Quakerbridge Road. The office is on the left, just before Costco.
  • The building is located just past the intersection of Youngs Road and Quakerbridge Road.

For Out-of-State Patients:
The Lawrenceville office is approximately 15 to 18 minutes from Trenton-Mercer Airport, making same-day travel convenient for patients flying in for consultations or procedures. The office is also an 8-minute drive from Hamilton Train Station, accessible via NJ Transit for patients traveling from North Jersey or New York City. Capital Health Medical Center in Hopewell is located 10 to 15 minutes away, providing nearby hospital resources.

Additional Locations

Performance Pain and Sports Medicine
Address: 4056 Quakerbridge Road, Suite 112, Lawrenceville, NJ 08648
Landmark: Building complex with Silver Pharmacy and Jag Physical Therapy
Nearby: Approximately one mile from Quakerbridge Mall
Phone: 609-588-8600

Insurance and Payment Options

Performance Pain and Sports Medicine accepts most major insurance plans for medically necessary pain management procedures, including diagnostic testing, injections, nerve blocks, and neuromodulation. FSA and HSA accounts can also be applied toward treatment costs.

Some regenerative procedures, including PRP therapy and the Discseel® Procedure, may be considered elective and are available on a cash-pay basis. For patients weighing this investment, the relevant consideration is often the cumulative cost of treatments that have provided only temporary relief compared to an approach that targets the underlying problem. Payment plans may be available for qualifying patients.

Contact the Lawrenceville office to verify your insurance coverage: 609-588-8600 | Request an appointment

Frequently Asked Questions About Pain Management in Lawrenceville

Most patients seek pain management when pain lasts beyond normal healing time, typically three to six months. Common qualifying conditions include chronic back pain, neck pain, joint pain, nerve pain, sciatica, and headaches. A referral is generally not required to schedule a consultation. If conservative treatments such as rest, physical therapy, or over-the-counter medications have not provided lasting relief, a pain management evaluation can help identify more targeted treatment options.

The Lawrenceville office offers a full range of interventional pain management procedures, including epidural steroid injections, facet joint injections, nerve blocks, radiofrequency ablation, spinal cord stimulation, and regenerative therapies such as PRP and the Discseel® Procedure. Each treatment plan is developed based on a thorough evaluation of the patient’s specific condition, imaging, and treatment history. The goal is always to target the source of pain using the least invasive approach that is clinically appropriate.

The Discseel® Procedure is a non-surgical, outpatient treatment that uses a biologic fibrin sealant to repair damaged spinal discs. It is designed for patients with disc degeneration, herniation, or annular tears who have not found lasting relief from conservative treatments but want to avoid spinal fusion. The procedure takes approximately 45 to 60 minutes, and most patients are discharged the same day. Dr. Wiederholz performs Discseel® at the Lawrenceville location, making it one of only two Performance Pain and Sports Medicine offices nationwide where this procedure is available.

Most major commercial insurance plans are accepted for medically necessary pain management procedures. FSA and HSA accounts may also be applied. Some elective and regenerative procedures are available on a cash-pay basis. The office staff can verify your specific benefits and explain any out-of-pocket costs before treatment begins. Call 609-588-8600 to confirm your coverage.

The first visit begins with a thorough review of medical history, imaging studies, and current symptoms. The physician performs a physical examination and discusses pain patterns, functional limitations, and treatment goals. Depending on the findings, additional diagnostic testing may be recommended. By the end of the visit, most patients leave with a clear understanding of what is causing their pain and a personalized treatment plan outlining the next steps.

Schedule Your Pain Management Consultation in Lawrenceville

If chronic pain is limiting your daily life, if other treatments have not provided lasting relief, or if you want to explore non-surgical options before considering surgery, the Lawrenceville team is ready to help. Patients who address chronic pain earlier often have access to a wider range of minimally invasive treatment options.

Take the first step toward relief:

The information on this page is for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Individual results may vary. Consult with your physician to determine the best treatment plan for your specific condition.

Last medically reviewed: April 2026 by Matthias Wiederholz, MD

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Performance Pain & Sports Medicine, LLC, is a premier non-surgical orthopedic institute providing a team-oriented approach to optimize your health and wellness.

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